Screening for phosphatidylinositol related-kinase inhibitors

Details Screening for phosphatidylinositol related-kinase inhibitors Screening for phosphatidylinositol related-kinase inhibitors

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/50 (2006.01)

Patent

CA 2292540

A method for identifying a compound inhibiting the phosphorylation activity of a phosphoinositide 3-kinase related kinase polypeptide is described. Antibodies having specific binding affinity for a conjugate including wortmannin are also described.

Cette invention concerne un procédé permettant d'identifier un composé qui inhibe l'activité de phosphorylation d'un polypeptide de kinase apparenté au phosphoinositide 3-kinase; ainsi que des anticorps présentant une affinité de liaison spécifique pour un conjugué comprenant du wortmannin.

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