Screening method for emulators of neural activity and...

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A61K 31/00 (2006.01) A61K 39/00 (2006.01) C07K 14/72 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2558721

The present invention primarily relates to function analysis of GPR35, an orphan GPCR (G protein coupled receptor), a screening method to identify modulators (agonists/antagonists) of the receptor, cells stably expressing the receptor, and the discovery of modulators of the receptor. The present invention also relates to novel rat GPR35.

La présente invention concerne d'abord l'analyse de fonction de GPR3, récepteur couplé à la protéine G orphelin, un procédé de recherche permettant d'identifier des démodulateurs (agonistes/antagonistes) de ce récepteur, des cellules exprimant de manière stable ce récepteur et la découverte de modulateurs de ce récepteur. Cette invention concerne aussi un nouveau récepteur GPR35 de rat.

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