Screening method for orthopoxvirus antivirals

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/37 (2006.01) G01N 33/542 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2472119

The focus of the present invention is an effective anti-poxvirus drug for use in treating or preventing human disease caused by pathogenic poxviruses. More particularly, the present invention relates to antiviral drugs that target the poxvirus proteinase responsible for core protein maturation, a step which is absolutely essential for the production and spread of infectious virions.

Le thème focal de la présente invention est un médicament anti-poxvirus efficace destiné à être utilisé dans le traitement ou dans la prévention d'une maladie humaine provoquée par des poxvirus pathogènes. Plus particulièrement, l'invention concerne des médicaments antiviraux ciblant la protéinase de poxvirus responsable de la maturation de la protéine du noyau, une étape qui est absolument essentielle à la production et à l'expansion de virions infectieux.

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