Screening method for periodontal disease

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/52 (2006.01) A61C 19/06 (2006.01)

Patent

CA 2199499

A method of screening for the presence of a periodontal disease condition is disclosed. The method involves obtaining an oral fluid sample from a human subject being tested, and determining the level of native free pyridinium crosslinks (free pyridinoline and/or free deoxypyridinoline) from the subject. An above-normal level of crosslinks, when compared with a predetermined level characteristic of normal subjects, is an indication of the presence of a periodontal disease condition.

Méthode de dépistage d'un état pathologique de la parodontolyse qui consiste à prélever un échantillon de liquide buccal chez un patient humain, à déterminer le taux de liaisons de pyridinium libre natif (pyridinoline et/ou désocypyridinoline) chez le sujet. Un niveau de liaisons au-dessus de la normale, par rapport à un niveau caractéristique prédéterminé chez des sujets normaux révèle la présence d'une parodontolyse pathologique.

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