Screening method involving mgdg synthase

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/48 (2006.01)

Patent

CA 2371987

The invention concerns a method for screening and selecting parasiticides (apicomplex phyllum parasites) and/or herbicides and the uses thereof. Said method consists in incubating a substance to be tested with a MGDG synthase and measuring the specific enzymatic activity, after said incubation. The invention also concerns the use of MGDG synthase or a plant isolated plastid membrane for selecting or screening the products inhibiting the activity of the MGDG synthase, capable of being used as active principles against apicomplex parasites and/or of being used as herbicides.

Procédé de criblage et de sélection d'antiparasitaires (parasites du phyllum des apicomplexes) et/ou d'herbicides et ses applications. Ledit procédé comprend: l'incubation d'une substance à tester avec une MGDG synthase et la mesure de l'activité spécifique enzymatique, après ladite incubation. L'invention concerne également l'utilisation d'une MGDG synthase ou d'une membrane plastidiale isolée de plante, pour la sélection ou le criblage de produits inhibiteurs de l'activité de la MGDG synthase, aptes à servir de principes actifs contre les parasites apicomplexes et/ou aptes à servir d'herbicides.

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