C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C07K 14/705 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2512444
A screening tool and a screening method of a substance which is useful as an agent for improving the memory, an agent for improving learning ability, and/or an antidementia agent; a polypeptide, a polynucleotide, a vector, and a cell which may be used in the above screening; and a novel agent for improving the memory, a novel agent for improving learning ability, and/or a novel antidementia agent are disclosed. The above screening tool is composed of a calcium-permeable nonselective cation channel or a cell expressing the channel.
Un outil de criblage et un procédé de criblage servent à obtenir une substance qui est utile en tant qu'agent améliorant la mémoire, un agent améliorant la capacité d'apprentissage et/ou un agent dirigé contre la démence; un polypeptide, un polynucléotide, un vecteur et des cellules qui peuvent s'utiliser dans ces procédés de criblage, et un nouvel agent améliorant la mémoire, un agent améliorant la capacité d'apprentissage et/ou un agent dirigé contre la démence. L'outil de criblage décrit ci-dessus comprend un canal de calcium non sélectif perméable au calcium ou des cellules qui l'expriment.
Inamura Kohei
Mochizuki Shinobu
Sano Yorikata
Astellas Pharma Inc.
Dennison Associates
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