C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2599792
The present invention is relates to non-diffusible globular A.beta.(X - 38 .. 43) oligomers ("globulomers") or derivatives thereof, methods for enriching said globulomers or derivatives, compositions comprising said globulomers or derivatives, antibodies and aptamers having specificity for said globulomers or derivatives, methods for preparing such antibodies and aptamers, uses of said globulomers or derivatives, or of said antibodies or aptamers for diagnostic, therapeutic and other purposes, and corresponding methods using said globulomers or derivatives, or said antibodies or aptamers.
L'invention concerne des oligomères globulaires A.beta.(X - 38... 43) ("globulomères") non diffusibles ou leurs dérivés, des méthodes servant à enrichir lesdits globulomères ou lesdits dérivés, des compositions contenant lesdits globulomères ou lesdits dérivés, des anticorps et aptamères possédant une spécificité pour lesdits globulomères ou lesdits dérivés, des méthodes servant à préparer ces anticorps et ces aptamères, les utilisations desdits globulomères ou desdits dérivés ou desdits anticorps ou desdits aptamères à des fins diagnostiques, thérapeutiques ou autres, ainsi que des méthodes correspondantes mettant en application lesdits globulomères ou lesdits dérivés, ou lesdits anticorps ou lesdits aptamères.
Barghorn Stefan
Ebert Ulrich
Hillen Heinz
Keller Patrick
Striebinger Andreas
Abbott Gmbh & Co. Kg
Torys Llp
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