Screening method using bnpi and dnpi

Details Screening method using bnpi and dnpi Screening method using bnpi and dnpi

G - Physics

01

N

G01N 33/94 (2006.01) A61P 29/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2450472

The invention relates to a method for identifying pain-controlling substances using BNPI and/or DNPI. The invention also relates to the use of compounds thus identified, of active agents that bind to BNPI and/or DNPI, of antibodies directed against BNPI and/or DNPI, of antisense nucleotides against BNPI and/or DNPI, or of BNPI and/or DNPI, or partial proteins thereof, in addition to the use of corresponding polynucleotides as medicaments for pain therapy and as diagnostic agents.

L'invention concerne un procédé de repérage de substances contrôlant la douleur, à l'aide des protéines BNPI et/ou DNPI. Cette invention concerne également l'utilisation de composés ainsi identifiés, de principes actifs se liant à BNPI et/ou DNPI, d'anticorps dirigés contre BNPI et/ou DNPI, de nucléotides antisens contre BNPI et/ou DNPI ou des protéines BNPI et/ou DNPI, ou protéines partielles de ces dernières, ou encore des polynucléotides correspondants comme médicaments dans la thérapie de la douleur et le diagnostic.

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