Screening methods employing zebrafish and the blood brain...

Details Screening methods employing zebrafish and the blood brain... Screening methods employing zebrafish and the blood brain...

G - Physics

01

N

G01N 33/50 (2006.01) A01K 67/027 (2006.01)

Patent

CA 2556680

Use of fish, in particular zebrafish, in screening for substances with an ophthalmological effect or biological effect on the brain or central nervous system and/or effect on a disease or disorder of the brain or central nervous system. Based on identification and characterisation of the blood brain barrier.

L'invention concerne l'utilisation d'un poisson, plus spécifiquement du poisson zèbre, pour le criblage de substances ayant une effet ophtalmologique ou un effet biologique sur le cerveau ou le système nerveux central et/ou un effet sur une maladie ou un trouble du cerveau ou du système nerveux central. Cette utilisation se base sur l'identification et la caractérisation de la barrière hémato-encéphalique.

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