Screening methods for compounds that affect melanogenesis

Details Screening methods for compounds that affect melanogenesis Screening methods for compounds that affect melanogenesis

G - Physics

01

N

G01N 33/50 (2006.01) C12Q 1/02 (2006.01) C12Q 1/26 (2006.01) G01N 33/68 (2006.01) C12N 9/02 (2006.01)

Patent

CA 2377163

Methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems are provided. The invention further relates to the pharmacologic and cosmetic uses of such compounds to reduce or increase the synthesis of melanin in animal and human melanocytes and melanocyte-derived cells.

L'invention concerne des procédés de criblage de composés ayant une incidence sur la mélanogénèse et sur la fonction de la protéine P dans les organismes, dans les cellules, ou dans les systèmes acellulaires. L'invention concerne également des utilisations pharmacologiques et cosmétiques de tels composés afin de réduire ou d'augmenter la synthèse de la mélanine dans des cellules de mélanocytes ou de dérivés de mélanocytes chez? ¿l'animal et chez l'homme.

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