Secondary amines

C - Chemistry – Metallurgy – 07 – D

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260/361.1, 260/3

C07D 307/80 (2006.01) C07D 307/81 (2006.01)

Patent

CA 1175851

ABSTRACT A compound of formula (I): Image wherein R1 and R2 are hydrogen or methyl, R3 is hydroxy, hydroxyalkoxy, benzyloxy or X- Y -Z wherein (i) X is a bond or oxygen, Y is C1-6 straight or branched alkylene, and Z is hydrogen or carboxy; or (ii) X is a bond or moiety -O-CH2-, Y is C2-6 straight or branched alkenylene, and Z is carboxy; and R4 is an option substituent, and n is 1, 2 or 3, their esters, amides and salts, are anti-obesity, hypoglycaemic, anti-inflammatory and platelet aggretation inhibiting agents.

385953

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