Secondary amines as renin inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/70 (2006.01) A61K 31/439 (2006.01) A61K 31/4418 (2006.01) A61P 9/00 (2006.01) C07D 211/34 (2006.01) C07D 401/14 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 451/02 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2637546

The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.

L'invention concerne de nouveaux dérivés d'amines secondaires de formule (I) et leur utilisation en tant que principes actifs dans la préparation de compositions pharmaceutiques. L'invention concerne également des aspects apparentés, parmi lesquels des procédés de préparation des composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés, et notamment leur utilisation en tant qu'inhibiteurs de la rénine.

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