C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/491, 260/578
C07C 49/76 (2006.01) C07C 33/20 (2006.01) C07C 45/29 (2006.01) C07C 45/59 (2006.01) C07C 229/38 (2006.01) C07D 317/16 (2006.01) C07D 317/30 (2006.01)
Patent
CA 1151203
- ABSTRACT - The compounds of formula (II): Image (II) in which R1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methyl- sulphonylamido, nitro, benzyloxy, methylsulphonyl- methyl, ureido, trifluoromethyl or p-methoxy- benzylamino group; R2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R3 18 a hydrogen, chlorine or bromine atom or a hydroxyl group, R4 is an alkyl group of 1 to 10 carbon atoms substituted by a hydroxyl, lower alkoxyl, oxo, lower acyloxy or OCH2CO2H group or lower alkyl ester thereof; R5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxy or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, ethyl or propyl group; R7 is a hydrogen atom or a methyl, ethyl or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond, have been found to possess anti-obesity and/or anti-hyper- glycaemic activity.
353753
Ainsworth Anthony T.
Smith David G.
Beecham Group Limited
Borden Ladner Gervais Llp
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