C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2653756
The present invention relates to compositions and methods of use thereof for cancer therapy sensitization. Such compositions comprise functional fragments of the nucleotide and/or polypeptide sequences of a Secreted Protein Acidic and Rich in Cysteine (SPARC). The compositions can be used in combination with existing chemotherapeutic agents for treatment of cancers.
La présente invention concerne des compositions et des procédés d'utilisation de ces compositions employés à des fins de sensibilisation dans le cadre de traitements anticancéreux. Ces compositions comportent des fragments fonctionnels des séquences nucléotidiques et/ou polypeptidiques d'une protéine secrétée acide et riche en cystéine (SPARC). Lesdites compositions peuvent être utilisées en association avec des agents chimiothérapeutiques existants pour traiter des cancers.
Smart & Biggar
The University Of British Columbia
LandOfFree
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