Secreted protein family

Details Secreted protein family Secreted protein family

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) A61P 15/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/08 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2522108

This invention relates to a new family of secreted proteins, termed the SECFAM3 family, its family members including the novel human proteins INSP123, INSP124 and INSP125, herein identified as secreted proteins containing a von Willebrand Factor type C (vWFC) domain, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.

L'invention concerne une nouvelle famille de protéines sécrétées, appelée famille SECFAM3, les membres de cette famille, tels que les nouvelles protéines humaines INSP123, INSP124 et INSP125, lesquelles ont été identifiées comme protéines sécrétées contenant un domaine du facteur de von Willebrand de type C (vWFC), ainsi que l'utilisation de ces protéines et des séquences d'acides nucléiques provenant des gènes codant pour celles-ci dans le diagnostic, la prévention et le traitement d'une maladie.

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