C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 31/00 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/485 (2006.01) C07K 16/18 (2006.01) C07K 16/22 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2516414
This invention relates to a new family of secreted proteins, termed the SECFAMI family, its family members including the novel proteins INSP113, INSP114, INSP115, INSP116 and INSP117, herein identified as secreted proteins containing epidermal growth factor (EGF) fold-containing domains, ranging from 125-153 amino acids in length and containing eight conserved cysteine residues and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
L'invention concerne une nouvelle famille de protéines sécrétées, à savoir la famille SECFAM1, dont les membres comprennent les nouvelles protéines INSP113, INSP114, INSP115, INSP116 et INSP117, identifiées comme protéines sécrétées renfermant des domaines contenant le facteur de croissance épidermique (EGF), allant de 125 à 153 acides aminés en longueur et renfermant huit résidus de cystéine préservés. Elle concerne également l'utilisation de ces protéines et de séquences d'acides nucléiques à partir de gènes codants dans le diagnostic, la prévention et le traitement de maladies.
Fagan Richard Joseph
Mckendrick Iain
Michalovich David
Power Christine
Yorke Melanie
Ares-Trading S.a.
Kirby Eades Gale Baker
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