Secure and efficacious therapy delivery for an...

A - Human Necessities – 61 – N

Patent

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A61N 1/39 (2006.01) A61N 1/00 (2006.01) A61N 1/365 (2006.01)

Patent

CA 2541392

An extra-systolic stimulation (ESS) therapy addresses cardiac dysfunction including heart failure. ESS therapy employs atrial and/or ventricular extra- systoles via pacing-level stimulation to a heart. These extra-systoles must be timed correctly to achieve beneficial effects on myocardial mechanics (efficacy) while maintaining an extremely low level of risk of arrhythmia induction and excellent ICD-like arrhythmia sensing and detection (security). The present invention relates to therapy delivery guidance and options for improved ESS therapy delivery. These methods may be employed individually or in combinations in an external or implantable ESS therapy delivery device.

Une thérapie de stimulation extrasystolique (ESS) traite le dysfonctionnement cardiaque, y compris l'insuffisance cardiaque. Cette thérapie ESS utilise des extrasystoles atriales et/ou ventriculaire via une stimulation du niveau de débit cardiaque. Ces extrasystoles peuvent être synchronisées correctement de façon à produire des effets bénéfiques sur des éléments mécaniques myocardique (efficacité) tout en maintenant un niveau de risque d'induction d'arythmie extrêmement bas et une détection d'arythmie de type IDC excellente (sécurité). Cette invention concerne aussi une conduite d'apport thérapeutique et des options permettant d'améliorer l'apport thérapeutique ESS. Ces techniques peuvent être utilisées individuellement ou en combinaison dans un dispositif d'apport thérapeutique ESS implantables ou externe.

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