Selectable herpes virus saimiri vectors for human cells

Details Selectable herpes virus saimiri vectors for human cells Selectable herpes virus saimiri vectors for human cells

C - Chemistry, Metallurgy

12

N

167/202, 195/1.2

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 15/869 (2006.01)

Patent

CA 1340448

Selectable Herpesvirus saimiri vectors which have a selection gene inserted into a junction region of the L- and H-DNA are described. Vectors of this type are able persistently to infect human T cells and thus are suitable for the expression of foreign genes in human T cells. An additional advantage is that no infectious virus particles are produced during this.

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