Selected 3-acylamino-5-[4(or 3)-pyridinyl] -...

Details Selected 3-acylamino-5-[4(or 3)-pyridinyl] -... Selected 3-acylamino-5-[4(or 3)-pyridinyl] -...

C - Chemistry, Metallurgy

07

D

260/279.4

C07D 213/75 (2006.01)

Patent

CA 1131231

Abstract of the Disclosure 3-Acyamino-5-[4(or 3)-pyridinyl]-2-(1H)-pyridinones or pharma- ceutically-acceptable acid-addition salts thereof useful as cardiotonic agents are prepared by reacting the corresponding 3-amino compound with an acylating agent providing acyl, where acyl is 2-acetoxypropanoyl, acetoacetyl or acetoxy- acetyl. Cardiotonic compositions and method for increasing cardiac contractil- ity using said 3-acylamino compounds as active component are disclosed.

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