Selected cgrp antagonists, method for producing the same and...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/4545 (2006.01) A61P 25/06 (2006.01) C07D 401/04 (2006.01) C07D 451/04 (2006.01) C07D 453/04 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01) C07D 487/08 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2562526

The invention relates to the CGRP antagonists of general formula (I), wherein A, X and R1 to R3 are defined as in claim 1. The invention also relates to the tautomers, diastereomers, enantiomers, hydrates, mixtures and salts thereof and to the hydrates of said salts, especially their physiologically acceptable salts with inorganic or organic acids, to drugs comprising said compounds, to their use and to a method for producing the same.

L'invention concerne les antagonistes CGRP de la formule générale (I) où A, X et R?1¿ à R?3¿ ont la définition donnée dans la revendication 1, leurs tautomères, diastérémères, énantiomères, hydrates, leurs mélanges et leurs sels ainsi que les hydrates des sels, notamment leurs sels physiologiquement compatibles avec des acides inorganiques ou organiques, les médicaments contenant ces composés, leur utilisation et leur procédé de production.

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