Selected cgrp-antagonists, their preparation processes and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/4184 (2006.01) A61K 31/4196 (2006.01) A61K 31/437 (2006.01) A61K 31/519 (2006.01) A61K 31/551 (2006.01) A61P 25/06 (2006.01) C07D 235/26 (2006.01) C07D 249/12 (2006.01) C07D 401/14 (2006.01) C07D 451/04 (2006.01) C07D 471/08 (2006.01) C07D 487/08 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2563386

CGRP-antagonists are disclosed having the general formula (I), in which A, X and R1-R3 have the definition given in claim 1, as well as their tautomers, diastereomers, enantiomers, hydrates, mixtures and salts, as well as their salt hydrates, in particular their physiologically compatible salts with inorganic or organic acids, medicaments containing these compounds, their use and their preparation processes.

La présente invention concerne les antagonistes CGRP de la formule générale (I) où A, X et R1 à R3 ont la définition donnée dans la revendication 1, leurs tautomères, diastéréomères, énantiomères, hydrates, leurs mélanges et leurs sels ainsi que les hydrates des sels, notamment leurs sels physiologiquement compatibles avec des acides organiques ou inorganiques, les médicaments contenant ces composés, leur utilisation et leur procédé de production.

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