Selection of colorectal cancer patients for neo-adjuvant and...

G - Physics – 01 – N

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G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2727559

The present invention relates to method for determining whether a gastrointestinal cancer patient is likely to experience a disease recurrence, said method comprising steps of determining concentration of TIMP-1 in a pre-operative plasma sample of said patient, and determining the concentration of CEA in a pre-operative body fluid sample of said patient, and evaluate whether the patient as likely to experience a disease recurrence.The present invention further provides kits for application of said methods.

La présente invention concerne un procédé de détermination du fait quun patient atteint dun cancer gastro-intestinal est susceptible de connaître une récurrence de la maladie, ledit procédé comprenant les étapes consistant à déterminer la concentration en TIMP-1 dans un échantillon de plasma préopératoire dudit patient, et à déterminer la concentration en CEA dans un échantillon de fluide biologique préopératoire dudit patient, et à évaluer si le patient est susceptible de connaître une récurrence de la maladie. La présente invention concerne en outre des kits dapplication desdits procédés.

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