C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/64 (2006.01) C07H 21/04 (2006.01) C12N 9/10 (2006.01) C12N 15/01 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/49 (2006.01) C12N 15/55 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2087519
(57) Abstract Using the method herein ribozymes are screened by culturing cells whose survival is dependent upon cleavage of RNA by a ribozyme within the cell. Cleavage by the ribozyme allows the cells to survive. The surviving cells are selected and contain the most effective ribozymes.
Drlica Karl A.
Dubnau David
Kramer Fred Russell
Pinter Abraham
Osler Hoskin & Harcourt Llp
The Public Health Research Institute Of The City Of New York Inc.
University Of Medicine And Dentistry Of New Jersey
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