A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 31/36 (2006.01) A61K 31/445 (2006.01) A61P 23/00 (2006.01)
Patent
CA 2442049
The present invention provides methods and kits for the selective ablation of pain-sensing neurons. The methods comprise administration of a vanilloid receptor agonist to a ganglion in an amount that causes death of vanilloid receptor-bearing neurons. Accordingly, the present invention provides methods of controlling pain and inflammatory disorders that involve activation of vanilloid receptor-bearing neurons.
La présente invention concerne des méthodes et des nécessaires servant à l'ablation sélective de neurones de sensibilité à la douleur. Ces méthodes consistent à administrer un agoniste du récepteur de vanilloïde à un ganglion, en quantité suffisante pour provoquer la mort des neurones porteuses du récepteur de vanilloïde. La présente invention concerne donc des méthodes pour maîtriser la douleur et les troubles inflammatoires impliquant l'activation de neurones porteuses du récepteur de vanilloïde.
Iadarola Michael J.
Karai Laszlo
Olah Zoltan
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Fetherstonhaugh & Co.
LandOfFree
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