Selective acylation process

Details Selective acylation process Selective acylation process

C - Chemistry, Metallurgy

07

D

260/20, 260/290.

C07D 213/74 (2006.01) C07D 401/04 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 1244822

Applicant: Aktiebolaget Leo Helsingborg, Sweden Inventors: Anders Robert Stamvik Sten Krister Kristensson Title: A selective acylation process Abstract of the This invention relates to a selective disclosure: acylation process for the preparation of phenolic N-disubstituted carbamate esters of steroids, comprising reacting in an inert solvent an acylating agent being a carbamoyl halogenide, a 4-(tertiary amino)-pyridine, or a complex thereof, op- tionally as a part of a polymer and a steroid having at least two free hydroxy groups, where at least one is phenolic and at least one is alcoholic, optionally in the presence of an acid acceptor.

464993

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