Selective analgesic agents

Details Selective analgesic agents Selective analgesic agents

C - Chemistry, Metallurgy

07

D

C07D 495/18 (2006.01) A61K 31/435 (2006.01) A61K 31/485 (2006.01) A61P 23/00 (2006.01) C07D 491/08 (2006.01) C07D 491/10 (2006.01) C07D 491/18 (2006.01) C07D 491/20 (2006.01) C07D 495/20 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2474306

The invention provides a method for producing a selective analgesic effect outside the brain (e.g. via opioid receptors in the spinal cord) of a mammal, comprising administering to the mammal, an effective analgesic dose of a compound that binds to delta-kappa opioid receptors in the mammal.

Cette invention a trait à une méthode de déclenchement d'une action analgésique sélective, en dehors du cerveau d'un mammifère, (par exemple par le biais de récepteurs d'opioïde dans la moelle épinière). Cette méthode consiste à administrer au mammifère une dose efficace analgésique d'un composé se fixant aux récepteurs des opioïdes .delta.-.kappa. dudit mammifère.

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