Selective androgen receptor modulators

Details Selective androgen receptor modulators Selective androgen receptor modulators

C - Chemistry, Metallurgy

07

D

C07D 271/10 (2006.01) A61K 31/421 (2006.01) A61K 31/4245 (2006.01) A61K 31/433 (2006.01) C07D 263/32 (2006.01) C07D 285/12 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2716320

This invention provides compounds of formulas H, Ia, H, and or salts thereof, pharmaceutical compositions comprising a compound of formulas H, Ia, H and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds of formulas H, Ia, H, and intermediates useful in the preparation of same. (I)

Cette invention porte sur des composés des formules (I), Ia, Ib, Ic, Id, Ie et/ou sur leurs sels, sur des compositions pharmaceutiques comprenant un composé des formules (I), Ia, Ib, Ic, Id, Ie et un excipient pharmaceutiquement acceptable, sur des procédés de modulation du récepteur de l'androgène, sur des procédés de traitement de maladies traitées de manière avantageuse par un modulateur du récepteur de l'androgène (par exemple, sarcopénie, cancer de la prostate, contraception, troubles ou maladies apparentées au diabète de type 2, anémie, dépression et maladie rénale) et sur des procédés de fabrication de composés des formules (I), Ia, Ib, Ic, Id, Ie et sur des intermédiaires utiles dans la préparation de ceux-ci.

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