Selective binding materials

G - Physics – 01 – N

Patent

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Details

G01N 33/543 (2006.01) C07K 1/22 (2006.01) G01N 33/531 (2006.01)

Patent

CA 2424637

A template (a molecule preferably of molecular size > 500 Da, or a larger entity such as a cell, virus or tissue sample) is dissolved or suspended in a fluid. The fluid is frozen, and the template is removed (e.g. by dissolution or electrophoresis, or mechanically) to leave an "imprinted" frozen fluid. This is capable of selectively adsorbing the template substance. It is usable as a separation medium, a recognition element in sensors and assays, and as a catalyst.

La présente invention concerne une matrice (molécule de préférence de taille moléculaire > 500 Da ou entité plus grande, telle qu'une cellule, un virus ou un échantillon de tissu), qui est dissoute ou mise en suspension dans un liquide. Ce liquide est congelé et la matrice est retirée (par exemple par dissolution, par électrophorèse ou de manière mécanique), afin de laisser un liquide congelé <= imprimé >=. Celui-ci peut adsorber de manière sélective la substance matrice et peut être utilisé en tant que milieu de séparation, en tant qu'élément de reconnaissance dans des détecteurs et dans des dosages et en tant que catalyseur.

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