Selective biologically active 7-oxo-prostacycline...

Details Selective biologically active 7-oxo-prostacycline... Selective biologically active 7-oxo-prostacycline...

C - Chemistry, Metallurgy

07

D

167/205, 260/235

C07D 307/935 (2006.01) C07D 407/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1246559

A B S T R A C T Racemic and optically active 7-oxo-prostacycline derivatives of the general formula Image I wherein R1 stands for hydrogen, C1-4 straight or branched alkyl or pharmacologically acceptable cation, R2 stands for hydrogen, C1-4 alkanoyl, benzoyl, or benzoyl substituted by C1-4 alkyl or halogen, and R2 can further represent tetrahydropyranyl, trialkyl silyl or alkoxy alkyl, A stands for ethylene, cis or trans-vinylene or -C=C- n may represent 2, 3 or 4.

473659

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