Selective, catalytic, and thermally induced...

C - Chemistry – Metallurgy – 07 – F

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C07F 5/02 (2006.01) B01J 31/12 (2006.01) B01J 31/14 (2006.01) B01J 31/22 (2006.01) C07B 47/00 (2006.01) B01J 23/46 (2006.01)

Patent

CA 2401695

A process for selectively functionalizing an aliphatic hydrocarbon and/or alkyl branched alicyclic hydrocarbon at a primary C-H hydrocarbon bond comprising thermally reacting a functionalizing reagent and the hydrocarbon in the presence of a catalyst, said catalyst comprising: a) a source of a transition metal; b) a source of a 3 to 8, cyclic or non-cyclic, aromatic or non-aromatic, neutral, cationic or anionic, substituted or unsubstituted, electron donor moiety which does not dissociate under thermal reaction conditions, wherein said moiety (i) lacks aromatic C-H bonds on the moiety directly bonded to the transition metal, or (ii) contains sterically hindered aromatic C-H bonds on the moiety directly bonded to the transition metal; and c) a source of ligands capable of formally donating an electron pair to the transition metal of a) and which dissociate thermally; and wherein said functionalizing reagent comprises a source of boron.

L'invention concerne un procédé destiné à fonctionnaliser de manière sélective un hydrocarbure aliphatique et/ou un hydrocarbure alicyclique alkyle ramifié au niveau d'une liaison d'hydrocarbure C-H primaire. Ce procédé consiste à faire réagir thermiquement un réactif fonctionnalisant et l'hydrocarbure en présence d'un catalyseur, ce catalyseur comprenant : a) une source de métal de transition, b) une source de fraction donneur d'électron de 3 à 8 chaînons, cyclique ou non cyclique, aromatique ou non aromatique, neutre, cationique ou anionique, substituée ou non substituée ne se dissociant pas dans des conditions de réaction thermique, cette fraction (i) manque de liaisons C-H aromatiques sur la fraction directement liée au métal de transition, ou (ii) contient des liaisons C-H aromatiques à encombrement stérique sur la fraction directement liée au métal de transition, et c) une source de ligands capable de donner formellement une paire d'électrons au métal de transition de a) et se dissociant thermiquement, le réactif de fonctionnalisation comprenant une source de bore.

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