Selective cyclooxygenase-2 anti-inflammatory eye drops

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/5415 (2006.01) A61K 9/08 (2006.01) A61K 31/18 (2006.01) A61K 31/405 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2332271

The present invention relates to an anti-inflammatory eye drop comprising a drug selectively inhibiting COX-2, selected from the group consisting of etodolac, N-(2-(cyclohexyloxy)-4-nitrophenyl) methane-- sulfonamide and meloxicam, which only slightly damages corneal epithelium and conjuctiva and which is excellent in the anti-inflammatory effect.

L'invention se rapporte à des gouttes oculaires anti-inflammatoires qui contiennent des agents chimiques susceptibles d'inhiber sélectivement COX-2. Lesdits agents sont sélectionnés dans le groupe constitué par étodolac, N-(2-(cyclohexyloxy)-4-nitrophényl)-méthanesulfonamide et méloxicam. Ces gouttes possèdent un excellent effet anti-inflammatoire et ne provoquent qu'une faible lésion épithéliale de la cornée ou une faible lésion de la conjonctive.

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