C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01) C07D 209/00 (2006.01) C07D 223/00 (2006.01) C07D 235/00 (2006.01) C07D 249/00 (2006.01) C07D 277/00 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2495879
The present invention provides compounds, which, are novel antagonists for D1/D5 receptors as well as methods for preparing such compounds. In another embodiment, the invention provides pharmaceutical compositions comprising such D1/D5 receptor antagonists as well as methods of using them to treat CNS disorders, obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
La présente invention concerne des composés qui sont de nouveaux antagonistes des récepteurs D1/D5, ainsi que des méthodes de préparation de tels composés. Dans un autre mode de réalisation, cette invention a trait à des compositions pharmaceutiques renfermant de tels antagonistes du récepteur D1/D5, ainsi qu'à des méthodes impliquant leur utilisation dans le traitement de troubles SNC, de l'obésité, des troubles métaboliques, des troubles de l'alimentation, tels que l'hyperphagie et les diabètes.
Burnett Duane A.
Greenlee William J.
Sasikumar Thavalakulam K.
Wu Wen-Lian
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
Schering Corporation
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