Selective estrogen receptor modulators

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/38 (2006.01) A61K 31/167 (2006.01) A61P 5/30 (2006.01)

Patent

CA 2538939

The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen receptor. Methods for making and using the disclosed SERMs are disclosed, including pharmaceutical formulations of the disclosed novel compounds in useful compositions.

La présente invention porte sur une nouvelle classe de modulateurs sélectifs du récepteur d'oestrogènes (SERM). Cette invention porte également sur l'identification d'une membrane jusqu'ici inconnue associée au récepteur d'oestrogènes. L'invention porte en outre sur des procédés de fabrication et d'utilisation de ces modulateurs (SERM), ainsi que sur des formulations pharmaceutiques de ces nouveaux composés dans des compositions utiles.

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