Selective inhibition of dna polymerase

Details Selective inhibition of dna polymerase Selective inhibition of dna polymerase

C - Chemistry, Metallurgy

07

K

C07K 16/08 (2006.01) C07K 7/06 (2006.01) C07K 14/035 (2006.01) C07K 16/40 (2006.01) C12N 9/22 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2011884

HX19 Abstract SELECTIVE INHIBITION OF DNA POLYMERASE Two peptides, P6 and P7, having the amino acid sequence APGDEPAPPY and AGATAEETRY have been used to obtain antibodies made against them, which antibodies specifically neutralize HSV-1 and HSV-2 DNA polymerase. The present invention also contemplates a method of screening for inhibitors of HSV-l and HSV-2 polymerase utilizing the antibodies.

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