Selective inhibitors for benzylaminoxidases with respect to...

Details Selective inhibitors for benzylaminoxidases with respect to... Selective inhibitors for benzylaminoxidases with respect to...

C - Chemistry, Metallurgy

07

C

167/228, 167/273

C07C 215/50 (2006.01) A61K 31/135 (2006.01) C07C 217/58 (2006.01)

Patent

CA 1303045

SELECTIVE INHIBITORS OF BENZYLAMINOXIDASES WITH RESPECT TO OTHER AMINOXIDASES ABSTRACT Selective inhibitors of benzylaminoxidases , said inhibitors consisting of compounds of the general formula I Image I wherein X is a group C-R4 or a nitrogen atom, R1 and R2, which can be the same or different from each other, represent hydrogen, hydroxyl groups, alkoxyl groups, or alkyl, alkenyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxyalkyl, hydroxyalkoxyl, alkoxyalkoxyl, hydroxyalkoxyalkoxyl, phenoxyl or phenoxyalkyl groups or their substitution derivatives in the phenoxyl group, provided that no more than one of the same be hydrogen, and one or more of the symbols R3, R4 or R5 are hydrogen atoms or alkyl or hydroxyl or alkoxyl or hydroxyalkyl or hydroxyalkoxyl or hydroxy- alkoxyalkyl or haloalkyl or carbonyl or carboxylic or ester or amldo or nitrile or sulfonic groups or halogen atoms or nitro groups.

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