Selective inhibitors of mmp-12

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/062 (2006.01) A61K 38/05 (2006.01) A61P 11/00 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/068 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2356919

The present invention provides novel mercaptoacetylamido dipeptide carboxylic acids of formula (1) which are MMP inhibitors useful for the treatment of smoking-induced emphysema.

Cette invention a trait à de nouveaux acides mercaptoacétylamido dipeptide carboxyliques correspondant à la formule (1) et qui sont des inhibiteurs de MMP utilisés pour le traitement de l'emphysème déclenché par la fumée du tabac.

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