Selective inhibitors of rock protein kinase and uses thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/04 (2006.01) A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2651836

Described herein are compounds that are useful as ROCK inhibitors. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including cardiovascular, inflammatory, neurological, or proliferative diseases or disorders.

L'invention concerne des composés utiles en tant qu'inhibiteurs ROCK. Ces composés, et des compositions pharmaceutiquement acceptables de ceux-ci, sont utiles dans le traitement ou l'atténuation de la gravité de divers troubles, tels que des maladies ou des troubles cardiovasculaires, inflammatoires, neurologiques, ou prolifératifs.

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