Selective inhibitors of viral or bacterial neuraminidase

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 309/28 (2006.01) C07D 211/72 (2006.01) C07D 211/92 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2546660

Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

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