A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2280134
A matrix metalloproteinase (MMP) inhibitor that exhibits an IC50 of below 10- 4M against MMP and has substantially no activity against non-MMP metalloproteinase-related events has reduced side-effects, especially with respect to joint pain.
L'invention concerne un inhibiteur de la métalloprotéase matricielle qui présente une concentration inhibitrice ¿50? de moins de 10?-4¿M contre la métalloprotéase matricielle, et n'exerce sensiblement aucune activité contre les évènements non liés à la métalloprotéase matricielle. Cet inhibiteur présente des effets secondaires réduits, en particulier, dans le domaine des douleurs articulaires.
Baxter Andrew Douglas
Bird John
Montana John Gary
Owen David Alan
Wills Ruth Elizabeth
Borden Ladner Gervais Llp
Darwin Discovery Limited
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