Selective reductive amination of nitriles

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 211/08 (2006.01) C07C 209/48 (2006.01) C07C 211/21 (2006.01) C07C 211/27 (2006.01) C07C 213/02 (2006.01) C07C 215/08 (2006.01) C07C 217/08 (2006.01)

Patent

CA 2323297

This invention pertains to an improvement in a process for the formation of secondary or tertiary amines by the catalytic reductive amination of a nitrite with a primary or secondary amine and, particularly to the reductive amination of C8- 20 nitrites with a secondary amine. The catalyst employed in the improved reductive amination process is one which has been promoted with a lithium salt or base, e.g., lithium chloride or lithium hydroxide.

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