C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/113 (2006.01) A61K 31/4162 (2006.01) A61K 31/4188 (2006.01) A61K 31/424 (2006.01) C07D 487/10 (2006.01) C07D 491/10 (2006.01) C07D 491/107 (2006.01) C07D 495/10 (2006.01) C07D 498/10 (2006.01)
Patent
CA 2522946
The present invention encompasses compounds of Formula (I) and Formula (II) or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
La présente invention concerne des composés de formule (I) et de formule (II), ou des sels ou des hydrates pharmaceutiquement acceptables desdits composés, utiles comme ligands des récepteurs aux glucocorticoïdes sélectifs pour le traitement d'une pluralité de maladies ou d'affections auto-immunes et inflammatoires. L'invention concerne également des compositions pharmaceutiques et des méthodes d'utilisation associées.
Ali Amjad
Balkovec James M.
Beresis Richard
Colletti Steven L.
Graham Donald W.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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