Selectively targeted antimicrobial peptides and the use thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/16 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) A61P 31/04 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2661634

The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.

La présente invention concerne le ciblage de peptides capables de se lier spécifiquement à des organismes microbiens (par exemple P. aeruginosa ou S. mutans), des peptides antimicrobiens ayant des activités antimicrobiennes, et des peptides antimicrobiens ciblés spécifiquement/sélectivement (STAMP). De plus, la présente invention fournit des procédés pour tuer sélectivement ou inhiber des micro-organismes en utilisant les peptides ou compositions fourni(e)s par la présente invention.

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