Selenium-containing merocyanine dyes

Details Selenium-containing merocyanine dyes Selenium-containing merocyanine dyes

C - Chemistry, Metallurgy

09

B

260/256, 260/382

C09B 23/10 (2006.01)

Patent

CA 1311758

NOVEL SELENIUM-CONTAINING MEROCYANINE DYES Abstract of the Disclosure A merocyanine dye having the formula: Image wherein: R1 and R2 independently are H, alkyl of 1-10 carbon atoms, alkoxy of 1-3 carbon atoms or phenyl or substituted phenyl, and any of R1 and R2, R1 and R7, and R2 and R8 can together comprise the atoms necessary to form a fused aromatic ring on the benzene radical to which they are attached; R5 and R6 comprise alkyl of from 1-18 carbon atoms provided that the sum of the carbon atoms in R5 and R6 is at least 8, or benzyl; R7 and R8 are H, or any pair of R7 and R1, R1 and R2 or R2 and R7 can comprise the atoms necessary to form together with the atoms on the benzene radical to which they are attached, a fused aromatic ring; R9 is an alkylene of 2-9 carbon atoms which can be interrupted by CONH; and Z+ is a cation selected from Na+, 1/2Ba2+ (C2H5)3NH+, K+, NH4+ and Li+. This dye is useful in a method for inactivating viruses comprising contacting the viruses with the compound and exposing the resulting mixture to visible light to excite and inactivate the viruses. The compounds are also useful in the irradiation-induced inactivation of leukemia cells.

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