Self-aligning peptides derived from elastin and other...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/78 (2006.01) A61K 8/64 (2006.01) A61L 27/00 (2006.01) A61L 27/34 (2006.01) A61L 31/10 (2006.01) A61Q 19/00 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2262446

A polypeptide is provided that has a secondary structure characterized by at least three beta-sheet/beta-turn structures, and that is not a naturally occurring fibrous protein. Such polypeptides, illustrated by one modeled on elastin, are useful in prosthesis.

L'invention concerne un polypeptide, lequel présente une structure secondaire, caractérisée par au moins trois structures à feuillet bêta/virage bêta, et n'est pas une protéine fibreuse naturelle. De tels polypeptides, à l'exemple d'un polypeptide construit sur le modèle de l'élastine, sont utiles dans des prothèses.

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