C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 9/127 (2006.01) A61K 31/7088 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2163364
A self-assembling polynucleotide delivery system comprises a dendrimer polycation aiding in the delivery of the polynucleotide to a desired address, and optionally other agents such as DNA masking agents, cell recognition agents, charge-neutralization agents, membrane- permeabilization agents, and subcellular-localization agents.
Système de libération de polynucléides à auto-assemblage, comprenant un polycation de dendrimères permettant de livrer plus facilement dans la zone souhaitée des polynucléides et, éventuellement d'autres agents tels que des agents de masquage pour ADN, des agents de reconnaissance cellulaire, des agents de neutralisation de la charge, des agents de perméabilisation de la membrane et des agents de localisation sous-cellulaire.
Haensler Jean
Szoka Francis C. Jr.
Smart & Biggar
The Regents Of The University Of California
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