Self-contained device integrating nucleic acid extraction,...

C - Chemistry – Metallurgy – 12 – M

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C12M 1/40 (2006.01) B01L 3/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2341687

A self-contained device (37, 43 and 46) is described that integrates nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequences which may be indicative of genetic defects or contagious diseases, as well as for monitoring efficacy in the treatment of contagious diseases.

La présente invention concerne un dispositif autonome (37, 43 et 46) qui intègre les fonctions d'extraction d'acides nucléiques, d'amplification de cibles spécifiques et de détection. Cette intégration des fonctions permet de détecter rapidement et avec précision des séquences d'acides nucléiques. Cette invention peut servir, par exemple, au criblage de séquences d'acides nucléiques pouvant révéler des anomalies génétiques ou des maladies contagieuses, ainsi qu'à la surveillance efficace du traitement dans le cas de maladies contagieuses.

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