Self-contained device integrating nucleic acid extraction,...

C - Chemistry – Metallurgy – 12 – M

Patent

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C12M 1/40 (2006.01) B01L 3/00 (2006.01) B01L 3/14 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2226717

A self-contained device is described that integrates nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequences which may be indicative of genetic defects or contagious diseases, as well as for monitoring efficacy in the treatment of contagious diseases.

La présente invention concerne un appareil unique et autonome qui intègre l'extraction de l'acide nucléique, l'amplification de cibles particulières et la détection. Cette intégration permet une détection rapide et précise des séquences nucléotidiques. L'invention peut être utilisée, par exemple, pour la recherche par criblage de séquences nucléotidiques qui peuvent être le signe de défauts génétiques ou de maladies contagieuses, ainsi que pour surveiller l'efficacité du traitement de maladies contagieuses.

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