Self-emulsifying active substance formulation and use of...

A - Human Necessities – 61 – K

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A61K 9/107 (2006.01) A61K 9/16 (2006.01) A61K 47/00 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2408915

The invention relates to self-emulsifying formulations based on an active substance constituent and on a formulation base with a lipid constituent and with a binding agent constituent. The invention also relates to the use of this formulation as a dosed form in the area of life science. The invention also relates to a method for producing self-emulsifying formulations by mixing the formulation constituents while forming a plastic mixture and optionally while preparing the formulations as a dosed form, advantageously while using melt extrusion. The formulations spontaneously form emulsions in water or in aqueous fluids.

L'invention concerne des formulations autoémulsifiantes à base d'un constituant principe actif et d'une base de formulation avec un constituant lipide et un constituant liant. L'invention concerne également l'utilisation de cette formulation sous forme dosée dans le domaine des sciences de la vie. L'invention concerne également un procédé permettant de préparer des formulations autoémulsifiantes par mélange des constituants de la formulation de manière à former un mélange plastique et éventuellement et à préparer les formulations sous forme dosée, avantageusement par extrusion par fusion. Dans l'eau ou dans des liquides aqueux, ces formulations forment spontanément des émulsions.

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