A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/355 (2006.01) A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 31/337 (2006.01)
Patent
CA 2478424
A pharmaceutical composition in a form of a self microemulsifying drug delivery system comprising: one or more therapeutic agent(s) which have low solubility in water of are water-insoluble, vitamin E, one co-solvent selected from propylene glycol and ethanol, one or more bile salts, TPGS, and one further surfactant selected from Tyloxapol and polyoxyl hydrogenated castor oil.
Cette invention se rapporte à une composition pharmaceutique se présentant sous la forme d'un système d'apport de médicament auto-micorémulsifiant et comprenant: un ou plusieurs agents thérapeutiques ayant une faible solubilité dans l'eau ou insolubles dans l'eau, de la vitamine E, un co-solvant choisi parmi le propylène glycol et l'éthanol, un ou plusieurs sels biliaires, du TPGS et un autre tensioactif choisi parmi le Tyloxapol et l'huile de ricin hydrogénée de polyoxyle.
Benita Simon
Garrigue Jean-Sebastien
Gursoy Neslihan
Lambert Gregory
Razafindratsita Alain
Novagali Pharma Sa
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Yissum Research Development Company Of The Hebrew University Of
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