A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/44 (2006.01) A61K 9/10 (2006.01) A61K 9/107 (2006.01) A61K 31/00 (2006.01) A61K 31/015 (2006.01) A61K 31/255 (2006.01) A61K 31/41 (2006.01) A61K 31/4196 (2006.01) A61K 31/44 (2006.01) A61K 31/4418 (2006.01) A61K 31/47 (2006.01) A61K 31/4706 (2006.01) A61K 31/4709 (2006.01) A61K 9/48 (2006.01)
Patent
CA 2455288
CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are self-emulsifying or self-microemulsifying, and comprise 1. a CETP inhibitor; 2. a cosolvent; 3. a surfactant having an HLB of 1 to 8; 4. a surfactant having an HLB of over 8 to 20; and 5. optionally, a digestible oil.
L'invention porte sur des inhibiteurs CETP qui présentent une meilleure solubilité et une meilleure biodisponibilité dans un excipient lipophilique comprenant une huile digestible, un solvant lipophilique, ou un agent de surface. Les compositions préférées sont auto-émulsifiantes ou auto-microémulsifiantes et comprennent : 1) un inhibiteur CETP, 2) un cosolvant, 3) un agent de surface présentant un HLB compris entre 1 et 8, 4) un agent de surface présentant un HLB compris entre 8 et 20, et 5) éventuellement, une huile digestible.
Gumkowski Michael Jon
Lombardo Franco
Murdande Sharad Balasaheb
Perlman Michael Ellis
Pfizer Products Inc.
Smart & Biggar
LandOfFree
Self-emulsifying formulations of cholesteryl ester transfer... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Self-emulsifying formulations of cholesteryl ester transfer..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-emulsifying formulations of cholesteryl ester transfer... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1413236